Gastrointestinal bleeding in the context of isolated factor VII deficiency: case report

Authors

  • Milagros Altamirano-Molina Servicio de Hematología, Hospital Nacional Guillermo Almenara Irigoyen. Lima, Perú. https://orcid.org/0000-0002-1071-212X
  • Alix X. Rivera-Pinto Asociación Científica de Estudiantes de Medicina de la Universidad Pedagógica y Tecnológica de Colombia. Bocaya, Colombia.
  • Carlos Julian Díaz-Torres Servicio de Hematología, Hospital Nacional Guillermo Almenara Irigoyen. Lima, Perú. https://orcid.org/0000-0002-8166-1315
  • William J Araujo-Banchon Grupo de Investigación Continental, Universidad Continental. Lima, Perú. https://orcid.org/0000-0002-5588-6860

Keywords:

Factor VII, prothrombin time, plasma, Peru.

Abstract

Introduction: Little is known about the acquired form of factor VII deficiency and few cases are reported in the literature.

Objective: To present a case of a patient with an isolated deficit of factor VII, in the context of low gastrointestinal bleeding.

Presentation of the case: 82-year-old Peruvian woman who comes to the emergency room for presenting with lower GI bleeding. Prolonged prothrombin time and isolated factor VII deficiency are detected during routine examinations. There were no evidence of pathological mechanisms of vitamin K deficiency or malabsorption, anticoagulant therapy with vitamin K antagonists, hyperfibrinolysis, or disseminated intravascular coagulation. She responded to the treatment with fresh frozen plasma and the normal results of the hematological test carried out on the sister remove the possible hereditary etiology.

Conclusion: This Peruvian case of isolated factor VII deficit, in the context of low gastrointestinal bleeding, allows adding information to the limited Latin American evidence.

 

Author Biographies

Milagros Altamirano-Molina, Servicio de Hematología, Hospital Nacional Guillermo Almenara Irigoyen. Lima, Perú.

Médico hematólogo

Alix X. Rivera-Pinto, Asociación Científica de Estudiantes de Medicina de la Universidad Pedagógica y Tecnológica de Colombia. Bocaya, Colombia.

Estudiante de medicina

Carlos Julian Díaz-Torres, Servicio de Hematología, Hospital Nacional Guillermo Almenara Irigoyen. Lima, Perú.

Médico hematólogo

William J Araujo-Banchon, Grupo de Investigación Continental, Universidad Continental. Lima, Perú.

Médico en ciencias en investigación epidemiológica

Published

2021-11-22

How to Cite

1.
Altamirano-Molina M, Rivera-Pinto AX, Díaz-Torres CJ, Araujo-Banchon WJ. Gastrointestinal bleeding in the context of isolated factor VII deficiency: case report. Rev Cubana Hematol Inmunol Hemoter [Internet]. 2021 Nov. 22 [cited 2024 Dec. 5];37(4). Available from: https://revhematologia.sld.cu/index.php/hih/article/view/1281

Issue

Section

Presentaciones de casos