Immunogenetic characterization of Cuban cadaveric donors in 2019

Authors

Keywords:

cadaveric donor, chronic renal failure, immunogenetics, kidney transplant.

Abstract

Introduction: Transplantation is the most favorable therapeutic option for people with chronic renal failure. The donor can be a cadaveric or living donor, related or not. Transplant outcomes are related to various immunological and non-immunological factors.

Objective: To characterize Cuban cadaveric donors for renal transplantation

Materials and methods: A cross-sectional and descriptive study of cadaveric donors was carried out during the year 2019. The region of origin, sex, skin color and age ranges of the donors were analyzed, as well as ABO and Rhesus Rh blood groups; serology for HIV, Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV), and toxic habits.

Results: A total of 95 cadaveric donors were studied, 62 from the West and 33 from the Center of the country. 63.2% were male and 36.8% female due to the most frequent age group being 40-60 years and the mean age of 49.45 years. 58.95% of the patients were of blood group O, 30.53% group A and groups B and AB had 5.26% prevalence; and only 8 were Rh negative. All had negative serology for HIV, HBV and HCV. The most frequent associated diseases were arterial hypertension and diabetes mellitus.

Conclusions: The cadaveric donors during the year 2019 showed characteristics similar to those reported by other studies. The increase in the age of the donors affects the appearance of associated diseases and this could affect the result of the transplant.

 

Published

2022-05-30

How to Cite

1.
Pérez Pérez M, Lima Dorta A de J, Morera Barrios LM, Figueras Suárez J del P, Valdés Coello R, Rodríguez Díaz E, et al. Immunogenetic characterization of Cuban cadaveric donors in 2019. Rev Cubana Hematol Inmunol Hemoter [Internet]. 2022 May 30 [cited 2025 Jan. 31];38(2). Available from: https://revhematologia.sld.cu/index.php/hih/article/view/1533

Issue

Section

Artículos Originales

Most read articles by the same author(s)

1 2 3 4 > >>