Pathophysiological characterization of autoimmune hemolytic anemia

Authors

Keywords:

autoimmune hemolytic anemia, RBC autoantibodies, autoimmunity, hemolysis, direct antiglobulin test.

Abstract

Introduction: Autoimmune hemolytic anemia is defined as increased destruction of red blood cells in the presence of autoantibodies directed against red cell blood group antigens. Objective: To characterize autoimmune hemolytic anemias, taking into account immunohematological, clinical, diagnostic and pathogenic mechanisms. Methods: A review of the literature, in English and Spanish, of articles published in the last 10 years on autoimmune hemolytic anemia was carried out. Conclusions: Autoimmune hemolytic anemia is a very heterogeneous disease. Diagnosis is usually easy, but difficult cases can be challenging. The definition of each type is fundamental since the therapy is different and focuses more on understanding the pathogenic mechanisms.

Author Biography

Gilberto Soler Noda, Instituto de Hematología e Inmunología. La Habana

Licenciado en Tecnología de la Salud, especialidad Medicina Transfusional. MSc. Bioquímica, mencion Inmunología, Profesor e Investigador Auxiliar, Miembro de la Sociedad Cubana de Hematología, Miembro de la Sociedad Cubana de Inmunología

Published

2022-11-28

How to Cite

1.
Soler Noda G. Pathophysiological characterization of autoimmune hemolytic anemia. Rev Cubana Hematol Inmunol Hemoter [Internet]. 2022 Nov. 28 [cited 2024 Dec. 18];38(4). Available from: https://revhematologia.sld.cu/index.php/hih/article/view/1715

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Section

Artículos de Revisión

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