Hematological alterations in peripheral blood of patients with COVID-19

Authors

  • Wilfredo Roque García Instituto de Hematología e Inmunología. La Habana. https://orcid.org/0000-0002-9442-5792
  • Ana María Simón Pita Instituto de Hematología e Inmunología. La Habana.
  • Yaquima Hernández Rego Instituto de Hematología e Inmunología. La Habana.
  • Katiuska Rodríguez García Instituto de Hematología e Inmunología. La Habana.
  • Rosa María Lam Díaz Instituto de Hematología e Inmunología. La Habana.

Keywords:

COVID-19, peripheral blood, complete blood count, cell morphology.

Abstract

Introduction: The first cases of atypical pneumonia of unknown etiology were reported in Wuhan, China in December 2019. In January 2020 a new virus from Coronaviridae family was described as causal agent and was named SARS-COV-2.

Objectives: To evaluate the clinical significance of numerical values of complete blood count (CBC) and morphologic changes on peripheral blood on patients with COVID-19.

Methods: A descriptive, observational, transversal study included patients with diagnosis of COVID-19 admitted in Freyre de Andrade Hospital in Havana, between June 1st and September 31st of 2022 was carried out. Patients were assigned to two groups according to their admission in intensive vigilance ward or intensive care unit. CBC test and peripheral blood smear were performed on admission day to evaluate the significance on clinical evolution.

Results: Female sex predominated on intensive vigilance group (67,36 %) and male in intensive care group (63,26 %). Media of age was superior in intensive care group (67,83 years). Leukocytosis and low level of platelets count were significantly more common in more severe group followed by lymphopenia. The presence of big platelets, cytoplasmic vacuoles and toxic granules were more common in intensive care unit group.

Conclusions: The CBC and peripheral blood smear are useful tools to diagnose and predict clinical evolution and allow a better management of infection.

 

Published

2023-06-27

How to Cite

1.
Roque García W, Simón Pita AM, Hernández Rego Y, Rodríguez García K, Lam Díaz RM. Hematological alterations in peripheral blood of patients with COVID-19. Rev Cubana Hematol Inmunol Hemoter [Internet]. 2023 Jun. 27 [cited 2024 Dec. 26];39(1). Available from: https://revhematologia.sld.cu/index.php/hih/article/view/1797

Issue

Section

HEMATOLOGÍA

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