Background of application of cell therapy as a health technology in medical and stomatological diseases

Authors

Keywords:

cell therapy, healthcare technology, hematopoietic stem cells, platelets, growth factors

Abstract

Introduction: During the last decades of the 20th century, cell therapy has been used in Cuba as a healthcare technology for alternative treatment of diseases.

Objective: To characterize the background of cell therapy application as a healthcare technology in medical and stomatological diseases.

Method: Seventy-two articles published between the years 2000 and 2022 from databases such as Scielo, Science Direct, Medline, and Pubmed were reviewed.

Analysis and synthesis of information: The utilization of cell therapy is linked to studies conducted on cells. There are three milestones: In 1838, the cell theory was postulated by Mathias Schleiden and Theodor Schwaan; in 1916, the first publication by Danchakoff to use the term "stem cell"; and in the early 2000s, regenerative medicine emerged as a distinct area within medical knowledge. Three stages were characterized: the first stage (1838-1915), the second stage (1916-1999), and the third stage (2000-Present), focusing on the development of new scientific evidence regarding the regenerative mechanisms of hematopoietic cells, platelets, and growth factors.

Conclusions: The conducted analysis enables the understanding of the origin, development, and current status of cell therapy application as a healthcare technology. This should have a transformative nature, integrating and enhancing contributions from basic, clinical, and surgical sciences to promote its widespread use as an alternative therapeutic approach in medical and stomatological diseases.

Author Biographies

Rosa Julia Robinson Rodríguez, Universidad Ciencias Medicas

Facultad medicina No 2

Irela Yolaidys Pérez Andrés, Universidad Ciencias Medicas

Ciencia y tecnica

Nadina Travieso Ramos, Universidad Ciencias Medicas

Ciencia y tecnica

Published

2024-08-07

How to Cite

1.
Robinson Rodríguez RJ, Pérez Andrés IY, Travieso Ramos N. Background of application of cell therapy as a health technology in medical and stomatological diseases. Rev Cubana Hematol Inmunol Hemoter [Internet]. 2024 Aug. 7 [cited 2025 Jan. 15];40. Available from: https://revhematologia.sld.cu/index.php/hih/article/view/1969

Issue

Section

MEDICINA REGENERATIVA

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