Spatial analysis of the incidence of acute lymphoid leukemia in children of Villa Clara, 2000-2019

Authors

Keywords:

Palabras clave, leucemia linfoide aguda, análisis espacial

Abstract

Introduction. Knowledge of the origin of acute lymphoid leukemia is limited; information is needed to allow the correct search for the etiological factor.

Objective. To determine the spatial distribution of acute lymphoid leukemia in children from Villa Clara, between 2000 and 2019.

Methods: A population-based descriptive epidemiological study was conducted. Data were obtained from the Population Registry and the National Cancer Registry. The Kulldorff technique was applied through the SaTScan Program, with the option of purely spatial retrospective analysis.

Results: The average anual incidence rate was 2.1 per 100,000. In children from 0 to 4 years old, and of these, those from the coastal area had rate of 4.8 and 8.1, respectively, the latter 2.36 times higher than those of the non-costal area. In children from 0 to 4 years old, the clusters included five of the six coastal municipalities; the most significant in Corralillo and Quemado de Güines, had a rate of 14,6 por 100000. Conjetures were made regarding the posible etiology. 

Conclusions: The risk of getting sick is higher in children from the coastal area of the province; this pattern is observed with marked clarity in the population aged 0 to 4 years old. A natural or anthropogenic factor, favored by existing conditions in that geographical area, in interaction with individual biological characteristics, typical of the first years of life, could be present in the etiology of the disease.

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Author Biography

Noira Durán Morera, Hospital Provincial Ginecobstétrico Universitario " Mariana Grajales". Villa Clara

Médico especialista en Medicina General Integral y en Bioestadística. Profesora Auxiliar de la Universidad de Ciencias Médicas de Villa Clara. Investigador agregado.

Published

2025-09-22

How to Cite

1.
Durán Morera N. Spatial analysis of the incidence of acute lymphoid leukemia in children of Villa Clara, 2000-2019. Rev Cubana Hematol Inmunol Hemoter [Internet]. 2025 Sep. 22 [cited 2025 Oct. 1];41. Available from: https://revhematologia.sld.cu/index.php/hih/article/view/2059

Issue

Section

HEMATOLOGÍA