Acute renal dysfunction in severe pediatric patients with acute lymphoid leukemia undergoing chemotherapy

Authors

Keywords:

Insuficiencias orgánicas; leucemia linfoide aguda.

Abstract

Introduction: Worldwide, acute renal dysfunction is a serious public health problem due to its high incidence, which varies with definitions and patients' comorbidities. The presence of this entity in severely ill children with acute lymphoid leukemia occurs in isolation or as part of multiple organ failure syndrome.

Objectives: To analyze acute renal dysfunction in seriously ill pediatric patients diagnosed with acute lymphoid leukemia.

Methods: A bibliographical-documentary research on the subject was carried out. The articles in Spanish and English published in the last five years in the SciELO and PubMed databases were consulted.

Analysis and synthesis of information: Characteristics derived from acute renal dysfunction are described, such as a rapid decrease in glomerular filtration rate, disorders in acid-base and electrolyte homeostasis, and the inability of the kidney to excrete nitrogenous products, which may be associated with chemotherapy treatment, with a large number of medical complications and high mortality.

Conclusions: With adequate monitoring of acute renal dysfunction, there is a decreased risk of complications and death in these patients.

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Author Biography

Juan Antonio Figueroa Saez, Escuela Nacional de Salud Pública

Profesor Universitario

Published

2026-03-08

How to Cite

1.
Figueroa Saez JA, Mamposo Valdés JC, Forrellat Barrios M. Acute renal dysfunction in severe pediatric patients with acute lymphoid leukemia undergoing chemotherapy. Rev Cubana Hematol Inmunol Hemoter [Internet]. 2026 Mar. 8 [cited 2026 Mar. 11];42:e2077. Available from: https://revhematologia.sld.cu/index.php/hih/article/view/2077

Issue

Section

HEMATOLOGÍA