Clinical and survival of patients with multiple myeloma in a state of Northeast Brazilian

Authors

  • Kalyane da Silva Ferreira Federal University of Rio Grande do Norte
  • Isabelle Campos de Azevedo Federal University of Rio Grande do Norte http://orcid.org/0000-0001-5322-7987
  • James Farley Rafael Maciel Liga Norteriograndense contra o Câncer
  • Diana Paula de Souza Rego Pinto Carvalho Federal University of Rio Grande do Norte
  • Allyne Fortes Vitor Federal University of Rio Grande do Norte
  • Marcos Antonio Ferreira Júnior Federal University of Rio Grande do Norte http://orcid.org/0000-0002-9123-232X

Keywords:

multiple myelomas, plasmacytoma, bone marrow, epidemiology

Abstract

Introduction: The annual prevalence of Multiple Myeloma in patients aged between 65 and 74 years old is 31 cases for every 100 000 people and increases to 46 cases per 100 000 people in patients older than 75 years old. Objectives: To clinically characterize patients with multiple myeloma treated at a referral center in the state of Rio Grande do Norte, Brazil, and to estimate their survival. Methods: Retrospective cohort study. For data collection, secondary sources listed in the cadastral database and complementation with data records was used. The descriptive analysis was performed by using the Epi Info program, version 3.5.2 and the survival analysis used Statistic Package for Social Sciences (SPSS) software version 22. Results: Out of the 39 patients studied, 17 (43.6%) were male, and 22 (56.4%) were female, with an average age of 66.3 years old. The main medication therapeutic regimen was the combination of Cyclophosphamide, Thalidomide, and Dexamethasone (CTD), as the most medical prescription used in 63.6% of cases. Only 38.5% had other comorbidities and 46.2% of patients developed plasmacytoma. In the International Staging System (ISS), stage III prevailed with 30.8% among the evaluated patients. The cumulative probability of global survival rate showed a disease with a survival rate of 50% of the sample in about 36 months (three years) after diagnosis is confirmed.

Author Biographies

Kalyane da Silva Ferreira, Federal University of Rio Grande do Norte

Nurse, Federal University of Rio Grande do Norte. Member of the Research Group "Núcleo de Estudos e Pesquisas em Enfermagem Clínica (NEPEC)", Natal/RN, Brazil.

Isabelle Campos de Azevedo, Federal University of Rio Grande do Norte

Nurse, Ph.D Student of the Program Graduate Nursing of the Federal University of Rio Grande do Norte. Member of the Research Group "Núcleo de Estudos e Pesquisas em Enfermagem Clínica (NEPEC)", Natal/RN, Brazil.

James Farley Rafael Maciel, Liga Norteriograndense contra o Câncer

Hematologist Medical Blood Center in Dalton Barbosa Cunha and Liga Norteriograndense contra o Câncer, Natal/RN, Brazil.

Diana Paula de Souza Rego Pinto Carvalho, Federal University of Rio Grande do Norte

Nurse, Doctor's Program Graduate Nursing of the Federal University of Rio Grande do Norte, CAPES Scholarship. Member of the Research Group "Núcleo de Estudos e Pesquisas em Enfermagem Clínica (NEPEC)", Natal/RN, Brazil.

Allyne Fortes Vitor, Federal University of Rio Grande do Norte

Nurse, PhD in Nursing, Teacher Course Undergraduate and Postgraduate Nursing Federal University of Rio Grande do Norte, Natal/RN, Brazil. Deputy Leader of the Research Group "Núcleo de Estudos e Pesquisas em Enfermagem Clínica (NEPEC)."

Marcos Antonio Ferreira Júnior, Federal University of Rio Grande do Norte

Nurse, Doctor of Health and Development, Teacher Course Undergraduate and Postgraduate Nursing Federal University of Rio Grande do Norte, Natal/RN, Brazil. Leader of the Research Group "Núcleo de Estudos e Pesquisas em Enfermagem Clínica (NEPEC)."

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Published

2017-02-17

How to Cite

1.
Ferreira K da S, Azevedo IC de, Maciel JFR, Carvalho DP de SRP, Vitor AF, Ferreira Júnior MA. Clinical and survival of patients with multiple myeloma in a state of Northeast Brazilian. Rev Cubana Hematol Inmunol Hemoter [Internet]. 2017 Feb. 17 [cited 2024 Dec. 12];33(2). Available from: https://revhematologia.sld.cu/index.php/hih/article/view/509

Issue

Vol. 33 No. 2 (2017): Abril - Junio

Section

Artículos Originales

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