Therapeutic news in chronic lymphoid leukemia

Authors

Keywords:

chronic lymphoid leukemia, overall survival, free life survival, treatment.

Abstract

Introduction: Chronic lymphoid leukemia is a chronic lymphoproliferative neoplasm characterized by the increase of a dysfunctional lymphoid clonal population with immunophenotype B (> 95%) and exceptionally T (<5%), it mainly affects people over 55 years of age, increasing towards the seventh decade of life.

Objective: To analyze the main therapeutic modalities for the management of chronic lymphoid leukemia.

Methods: A literature review was carried out, in English and Spanish, through the PubMed website and the academic search engine Google for articles published in the last 5 years. An analysis and summary of the revised bibliography was made.

Analysis and synthesis of the information: Chronic lymphoid leukemia was considered for decades a disease of the elderly patient, generally of an indolent course, unpredictable and incurable evolution. The treatment of this disease has undergone in the last 30 years very significant changes that have had a favorable impact on the increase in the overall and disease-free survival of patients who suffer from it.

Conclusion: Adequate follow-up of patients with chronic lymphoid leukemia must be maintained, as this will make it possible to reduce complications, progression and increase overall survival as much as possible.

 


Author Biographies

Yusleidy Concepción Fernández, Instituto de Hematología e Inmunología

Especialista de 1er Grado en MGI y Hematología Investigador Agregado

Yamilé Quintero Sierra, Instituto de Hematología e Inmunología

Especialista de primer grado en MGI. Especialista de segundo grado en Hematología. Máster en enfermedades Infecciosas.Profesor Instructor. Investigador auxiliar

Adrian Romero González, Instituto de Hematología e Inmunología

Especialista de primer grado en MGI. Especialista de segundo grado en Hematología. Profesor Auxiliar. Investigador auxiliar.

Published

2021-07-13

How to Cite

1.
Concepción Fernández Y, Quintero Sierra Y, Romero González A. Therapeutic news in chronic lymphoid leukemia. Rev Cubana Hematol Inmunol Hemoter [Internet]. 2021 Jul. 13 [cited 2024 Dec. 12];37(3). Available from: https://revhematologia.sld.cu/index.php/hih/article/view/1344

Issue

Section

Artículos de Revisión

Most read articles by the same author(s)

1 2 3 4 > >>