Antimicrobial sensitivity and resistance of staphylococci from skin lesions of patients with acne vulgaris

Authors

Keywords:

acné vulgar, microbiota cutánea, resistencia bacteriana.

Abstract

Introduction: The study of the skin microbiota is essential in acne, especially when there is evidence that implicates chronicity and severity with dysbiosis.

Objective: To determine the antimicrobial sensitivity and resistance of staphylococci from skin lesions of patients with acne vulgaris.

Methods: A descriptive, cross-sectional study was carried out at the Amalia Simoni Teaching Clinical-Surgical Hospital in Camagüey, between January 2023 and June 2024. The universe consisted of 76 patients with skin lesions of acne vulgaris and the sample consisted of 54 with growth of staphylococci of the species S. aureus and S. epidermidis.

Results: Co-isolation of S. aureus and S. epidermidis was obtained in 63%. S. aureus showed a pattern of resistance to multiple antibiotics, with the highest resistance being to amoxicillin (95.5%), penicillin (90.9%), and cephalexin (77.7%). The highest susceptibility was to trimethoprim/sulfamethoxazole (63.6%), followed by ciprofloxacin (56.8%). S. epidermidis revealed a pattern of highest susceptibility with 100% to trimethoprim/sulfamethoxazole, 91.3% to ciprofloxacin, and 87% to gentamicin. The highest resistance was to penicillin and amoxicillin with 60.9%, followed by cephalexin with 52.2%.

Conclusion: S. aureus and S. epidermis are actively involved in acne, with resistance patterns to multiple antibiotics, among which penicillins and cephalosporins stand out for their high percentages. The greatest sensitivity for both bacteria is obtained to trimethoprim/sulfamethoxazole and ciprofloxacin.

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Author Biographies

Edilberto Machado del Risco, Hospital Clínico Quirúrgico Docente Amalia Simoni, Camagüey

Graduado de medicina 1991, Graduado de especialista de Primer Grado en Alergia en 1997 y Segundo Grado en alergia en 2010, Jefe de Grupo Provincial de Alergia en Camagüey

Cira Cecilia León Ramentol, Centro de Inmunología y Productos Biológicos. Universidad de Ciencias Médicas de Camagüey

Especialista de Primer Grado en Medicina General Integral y Primer y Segundo Grado en Laboratorio Clínico. Dr. C. en Ciencias Médicas. M. Sc. en Enfermedades Infecciosas. Investigador Auxiliar, Profesor Titular. Universidad de Ciencias Médicas de Camagüey

Elizabeth Nicolau Pestana, Centro de Inmunología y Productos Biológicos. Universidad de Ciencias Médicas de Camagüey

Licenciada en Biología. M. Sc. en Bacteriología-Micología. Investigador Agregado. Profesor Auxiliar. Universidad de Ciencias Médicas de Camagüey. Directora del Centro de Inmunología y Productos Biológicos.

Niurka García Cruz, Hospital Amalia Simoni

Técnico de microbiología desde 1985 labora en el Hospital amalia Simoni

Published

2025-09-22

How to Cite

1.
Machado del Risco E, León Ramentol CC, Nicolau Pestana E, García Cruz N. Antimicrobial sensitivity and resistance of staphylococci from skin lesions of patients with acne vulgaris. Rev Cubana Hematol Inmunol Hemoter [Internet]. 2025 Sep. 22 [cited 2025 Nov. 26];41. Available from: https://revhematologia.sld.cu/index.php/hih/article/view/2105

Issue

Section

INMUNOLOGÍA